Hi guys! I have the same problem since a few month and I can't find the solution.
My vcenter server is in:
OS. Windows Server 2012 R2 Standard
DB: Microsoft SQL Server Enterprise 11.0.2100.60
VCenter Version: Versión 6.5.0 Compilación 5318154 (18 APRIL 2017)
Also I had the same problem in oldest versions (4602587 and 4944578).
As a temporaly solution I delete de profile folders from C:\ProgramData\VMware\vCenterServer\data\vSphere Web Client\SerenityDB\serenity, after delete the profile folders works.
But I need to fix it definitly because crash frecuently.
I checked the GPO and not all user are add, and I cound't add it. hi users I couldn't add because doesn´t exist in my server.
content-library
perfcharts
vmware-vpostgres
vsan-health
The IPv6 is disabled in my Vcenter Server,
The DNS is correct in my DC ( register A and PTR)
The host file it's empty.
Someone can help me?
Sorry for my poor English, my native language is Spanish
Regards.
Patricio.